Top Biomarkers for Longevity: What to Track First
Longevity is built on measurable biology. The right biomarkers help you understand cellular energy, resilience, and the systems that shape long-term health.
“Longevity biomarkers” are measurements that reflect how well your body maintains function over time. Rather than relying on symptoms alone, biomarkers allow you to quantify key drivers of health—especially those tied to energy, recovery, and metabolic stability.
1) NAD+ (cellular energy & resilience)
NAD+ plays a central role in cellular energy production and supports biological processes linked to healthy aging. Tracking NAD+ can provide insight into how efficiently your cells produce energy and maintain long-term resilience.
Read: NAD+ levels — why this molecule matters for energy and longevity
2) Magnesium (energy metabolism & recovery)
Magnesium supports hundreds of enzymatic reactions, including those involved in energy metabolism, muscular function, and recovery. Low magnesium status can affect fatigue and performance over time.
3) Zinc (immune balance & cellular function)
Zinc is essential for immune regulation, protein synthesis, and cellular repair mechanisms. Monitoring zinc can help ensure your baseline supports long-term resilience.
4) Selenium (antioxidant systems & thyroid support)
Selenium contributes to antioxidant defense systems and supports key metabolic pathways. Maintaining adequate levels is part of a stable, longevity-oriented foundation.
5) The “trend” biomarker that matters most: change over time
One measurement can be informative, but trends are more powerful. The most important longevity signal is often whether your biomarkers are moving in the right direction as your lifestyle evolves.
How to choose biomarkers based on your goal
- Energy & fatigue: prioritize NAD+ and magnesium status.
- Resilience & immunity: consider zinc and selenium status.
- Long-term tracking: test consistently and compare timepoints.
Biostarks: start with measurement
Biostarks helps you establish an objective baseline and understand your biomarkers with a science-driven approach. The goal is clarity: know what to optimize, and track what changes.
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FAQ
What are the best biomarkers for longevity?
The best biomarkers are the ones that reflect core systems: cellular energy, metabolic stability, and resilience— and that you can track consistently over time.
Should everyone track the same biomarkers?
Not necessarily. The most relevant biomarkers depend on your lifestyle, training load, recovery, and goals. A baseline test helps you prioritize.
How often should longevity biomarkers be measured?
Many people track every 3–6 months while optimizing, then periodically for maintenance. The key is consistent conditions.







